The MSK- imaging research unit aims to implement, test, develop and potentially improve the use of various imaging techniques to diagnose, follow treatment responses and understand the underlying patho-physiology and anatomy of various musculoskeletal diseases.
Our research is done in close collaboration with several internal and external departments and collaborators (see collaborators below) and focuses on-, and covers a large variety of musculoskeletal conditions including osteoarthritis, rheumatoid arthritis, psoriatic arthritis, generalised pain syndromes, degenerative and inflammatory diseases of the spine (axial spondylosis/spondylitis), tendon diseases and sports related injuries etc.
All of these conditions can affect most joints and soft issues in the body including muscles and tendons and impose a substantial burden on the affected individual and the society.
We see our self as pioneers in the use of novel imaging methods to quantify inflammation in both inflammatory and degenerative MSK diseases including muscles and tendons, primarily using static and dynamic contrast enhanced MRI (DCE-MRI), but we also in a joint venture with the Parker institute, the Danish research center for MRI at Hvidovre university hospital and Rigshospitalet, use functional MRI (fMRI) of the brain to understand the individual patients response to pain, and finally we use the first tilting weight baring MRI scanner in Scandinavia to understand the mechanical changes in the lumbar spine, the knees and feets with the aim of to clarify the impact of mechanical changes from supine to weightbaring on the clinical pain syndromes .
Finally we use imaging as inclusion criteria’s as well as both primary and secondary end-point in studies testing pharmacological therapy, impact of weight loss, herbal food supplements, in collaborations with national and international research groups and the pharmaceutical industry.
Since most of our research focuses on implementing and testing novel imaging techniques in clinical research our results has the potential to be relatively fast and easy translated into clinical practice to the benefit of the individual patient.
We also take an active part in research training, educational activities of pre- and post-graduate students and fellows, and encourage them to participate in our research.
For information about possible attachment to the imaging unit as a pre- or postgraduate student (Bachelor, Master, or PhD) please contact the unit head Mikael Boesen, or the responsible research technician Janus Damm Nybing.
The Department of Radiology of BFH has at Bispebjerg Hospital one GE 1.5T and one Siemens 3T MR scanner, and at Frederiksberg Hosptital one 1.5T Philips, one 3T Siemens and one 0.25 tilting weightbaring MRI scanner, the G-scanner.
The 3T Siemens MRI scanner and the 0.25 tilting weightbaring MRI scanner, the G-scanner, was donated to the Parker institute by the OAK foundation in 2008 and installed and run by the department of Radiology Frederiksberg Hospital in 2008 (3T) and 2010 (G-scan).