2011

​Doctoral dissertations & PhD-theses:

Berentzen TL. PhD thesis: Changes in Waist Circumference: Prospective studies on the risk of diabetes, coronary heart disease and mortality. Institute of Preventive Medicine, Copenhagen Capital Region. Faculty of Health Sciences, University of Copenhagen. pp 1-47 + papers. Public defence January 18th, 2011. 

Brødsgaard A. PhD thesis: A childhood with or without overweight - Mother's action competence, health behaviour and relationships with their children. Faculty of Health Sciences, University of Southern Denmark. Institute of Preventive Medicine, Copenhagen Capital Region. pp 1.107 + papers. Public defence July 6th, 2011. 

Hare-Bruun H. PhD thesis: Food patterns in relation to health, lifestyle, and socioeconomic status. Research Unit for Dietary Studies, Institute of Preventive Medicine; Faculty of Health Sciences, University of Copenhagen. pp 1-71 + papers. Public defence Sept 26th, 2011. 

Knop J. Doctoral Dissertation: The Danish longitudinal study of alcoholism 1978-2008. A clinical high-risk study. Institute of Preventive Medicine, Copenhagen Capital Region. Faculty of Health Sciences, University of Copenhagen. pp 1-70. Public defence April 12th, 2011.

Pers T. PhD thesis: Integrative systems biology: elucidating complex traits. DTU Systems Biology; Institute of Preventive Medicine: pp 1-37 + papers. Public defence Sept 5th, 2011. 

Simonsen MK. PhD thesis: Intentional weight loss and mortality. Institute of Preventive Medicine, Copenhagen University Hospital. Faculty of Health Sciences, University of Copenhagen. pp 1-82 + papers. Public defence May 9th, 2011. 


Scientific papers:

Adegboye ARA, Anderssen SA, Froberg K, Sardinha LB, Heitmann BL, Steene-Johannessen J, Kolle E, Andersen LB. Recommended aerobic fitness level for metabolic health in children and adolescents: a study of diagnostic accuracy. Br J Sports Med. 2011;45:722-728.

Ajslev TA, Andersen CS, Gamborg M, Sørensen TIA, Jess T. Childhood overweight after establishment of the gut microbiota - the role of delivery mode, pre-pregnancy weight, and early administration of antibiotics. Int J Obes. 2011;35:522-529.

Andersen CS, Gamborg M, Sørensen TIA, Nøhr EÅ. Weight gain in different periods of pregnancy and offspring’s body mass index at 7 years of age. Int J Ped Obes. 2011;6:e179-e186.

Baker JL, Sørensen TIA. The Copenhagen School Health Records Register. Scand J Pub Health. 2011;39(Suppl 7):87-90. 

Baker JL, Sørensen TIA. Obesity research based on the Copenhagen School Health Records Register. Scand J Pub Health. 2011;39
(Suppl 7): 196-200. 

Banasik K, Justesen JM, Hornbak M, Krarup NT, Gjesing AP, Sandholt CH, Jensen TS, Grarup N, Andersson Å,  Jørgensen T, Witte DR, Sandbæk A, Lauritzen T, Thorens B, Brunak S, Sørensen TIA, Pedersen O, Hansen T.Bioinformatics-driven identification and examination of candidate genes for non-alcoholic fatty liver disease. PLoS One. 2011;6:e16542.2011.

Berentzen TL, Jakobsen MU, Halkjær J, Tjønneland A, Sørensen TIA, Overvad K. Changes in waist circumference and the incidence of diabetes in middle-aged men and women. PLoS One. 2011:6:e23104.

Berentzen TL, Jakobsen MU, Stegger JG,  Halkjaer J, Tjønneland A, Sørensen TIA, Overvad K.Changes in waist circumference and the incidence of acute myocardial infarction in middle-aged men and women PLoS One. 2011;6:e26849.

Brødsgaard A, Wagner L, Peitersen B, Poulsen I, Sørensen TIA. Maternal and child awareness and expectations of child overweight. Obes Facts. 2011;4:297-304.

Brødsgaard A, Wagner L, Peitersen B, Poulsen I, Sørensen TIA. Child overweight – mothers’ competence to take action. Obes Facts. 2011;4:305-311.

Dahm CC, Gorst-Rasmussen A, Jakobsen MU, Schmidt EB, Tjønneland A, Sørensen TIA, Overvad K. Adipose tissue fatty acid patterns and anthropometry in the Diet, Cancer and Health study. PLoS One. 2011;6:e22587. 

Drobnjak D, Taarnhøj NCBB, Mitchell P, Wang JJ, Tan A, Kessel L, Hougaard JL, Sørensen TIA, Larsen M. Heritability of optic disc diameters: a twin study. Acta Ophthalmol. 2011;89:e193-e198.

Du H, Vimaleswaran KS, Ängquist L, Hansen RD, van der A DL, Holst C, Tjønneland A, Overvad K, Jakobsen MU, Boeing H, Meidtner K, Palli D, Masala G, Saris WHM,  Feskens EJM, Wareham NJ, Sørensen TIA, Loos RJF. Genetic polymorphisms in the hypothalamic pathway in relation to subsequent weight change - the DiOGenes study. PLoS One. 2011;6:e17436.

Flensborg-Madsen T, Becker U, Grønbeck M, Knop J, Leo S, Mortensen EL.Alcohol consumption and later risk of hospitalization with psychiatric disorders: Prospective cohort study. Psych Res. 2011;187:214-219. 

Fontaine KR, Robertson HT, Holst C, Desmond R, Stunkard AJ, Sørensen TIA, Allison DB. Is socioeconomic status of the rearing environment causally related to obesity in the offspring? PLoS One. 2011;6:e27692.

Freathy RM, Kazeem GR Morris RW, Johnson PCD, Paternoster L, Ebrahim S, Hattersley AT, Hill A, Hingorani AD, Holst C, Jefferis BJ, Kring SII, Mooser V, Padmanabhan S, Preisig M, Ring SM, Sattar N, Upton MN, Vollenweider P, Waeber G, Sørensen TIA, Frayling TM, Watt G, Lawlor DA, Whincup PH, Tozzi T, Smith GD, Munafo M. Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index. Int J Epidemiol. 2011;40:1617-1628.

Gamborg M, Jensen GB, Sørensen TIA, Andersen PK. Dynamic path analysis in life course epidemiology. Am J Epidemiol. 2011;173:1131-1139.

Geller F, Feenstra B, Zhang H, Shaffer JR, Hansen T, Esserlind A-L, Boyd HA, Nohr EA, Timpson NJ, Fatemifar G, Paternoster L, Evans DM, Weyant RJ, Levy SM, Lathrop M, Smith GD, Murray JC, Olesen J, Werge T, Marazita ML, Sørensen TIA, Melbye M. Genome-wide association study identifies four loci associated with eruption of permanent teeth. PLoS Genet. 011;7:E1002275.

Goyenechea E, Holst C, Saris WH, Jebb S, Kafatos A, Pfeiffer A, Handjiev S, Hlavaty P, Stender S, Larsen TM, Astrup A, Martinez JA; on behalf of DIOGenes. Effects of different protein content and glycemic index of ad libitum diets on diabetes risk factors in overweight adults: the DIOGenes multicentre, randomised, dietary intervention trial.Diabetes Metab Res Rev. 2011;27:705-716.

Grau K, Tetens I, Bjørnsbo KS, Heitmann BL. Overall glycaemic index and glycaemic load of habitual diet and risk of heart disease. Pub Health Nutr. 2011;14:109-118.

Gögebakan Ö, Kohl A, Osterhoff MA, van Baak MA, Jebb SA, Papadaki A, Martinez JA, Handjieva-Darlenska T, Hlavaty P, Weickert MO, Holst C, Saris WHM, Astrup A, Pfeiffer AFH. Effects of weight loss and long-term weight maintenance with diets varying in protein and glycemic index on cardiovascular risk factors: The Diet, Obesity, and Geses (DiOGenes) Study: A randomized, controlled trial. Circulation. 2011;124:2829-2838.

Halkjær J, Olsen A, Overvad K, Jakobsen MU, Boeing H, Buijsse B, Palle D, Tognon G, Du H, van der A DL, Forouhi NG, Wareham NJ, Feskens EJM, Sørensen TIA, Tjønneland A. Intake of total, animal and plant protein and subsequent changes in weight or waist circumference in European men and women: the Diogenes project. Int J Obes. 2011;35:1104-1113.

Hansen TS, Jess T, Vind I, Elkjær M, Nielsen MF, Gamborg M, Munkholm P. Environemntal factors in inflammatory bowel disease: A case-controlled study based on a Danish inception cohort. J Crohns Colitis. 2011;5:577-584. 

Hare-Bruun H, Togo P, Andersen LB, Heitmann BL. Adult food intake patterns and the importance of present and childhood socioeconomic status. J Nutr. 2011;141:928-934.

Hare-Bruun H, Nielsen BM, Kristensen PL, Moller NC, Togo P, Heitmann BL. Television viewing, food preferences, and food habits among children:
A prospective epidemiological study. BMC Public Health. 2011;11:311.

Heitmann BL, Lissner L. Hip Hip Hurrah! Hip size inversely related to heart disease and total mortality. Obes Rev. 2011;12:478-481. 

Holm J-C, Gamborg M, Bille DS, Grønbæk HN, Ward LC, Faerk J. Chronic care treatment of obese children and adolescents. Int J Ped Obes. 2011;6:188-196.

Holm J-C, Gamborg M, Ward L, Gammeltoft S, Ibsen KK, Heitmann BL, Sørensen TIA. Tracking of leptin, soluble leptin receptor, and free leptin index during weight loss and weight regain in children. Obes Facts. 2011;4:461-468.

Hooton H, Dubern B, Henegar C, Paternoster L, Nøhr EA, Alili R, Rousseau F, Pelloux V, Galan P, Hercberg S, Arner P, Sørensen TIA, Clément K. Association between CST3 rs2424577 polymorphism and corpulence related phenotypes during lifetime in populations of European ancestry. Obes Facts. 2011;4:131-144.

Hornbak M, Banasik K, Justesen JM, Krarup NT, Sandholt CH, Andersson A, Sandbaek A, Lauritzen T, Pisinger C, Witte DR, Sørensen TIA, Pedersen O, Hansen T. The minor C-allele of rs2014355 in ACADS is associated with reduced insulin release following an oral glucose load. BMC Med Genet. 2011;12:4. 

Jakobsen MU, Dethlefsen C, Due KM, .........., Sørensen TIA, .........., Riboli E, Peeters PHM, Overvad K. Plasma phospholipid long-chain n-3 polyunsaturated fatty acids and body weight change. Obes Facts. 2011;4:312-318.

Jensen MK, Pers TH, Dworzynski P, Girman CJ, Brunak S, Rimm EB. Protein interaction-based genome-wide analysis of incident coronary heart disease. Circ Cardiovasc Genet. 2011;4:549-556.

Jess T, Simonsen J, Nielsen NM, Jørgensen KT, Bager PM, Ethelberg S, Frisch M. Enteric Salmonella or Campylobacter infections and the risk of inflammatory bowel disease. Gut. 2011;60:318-324.

Jiao H, Arner P, Hoffstedt J, Brodin D, Dubern B, Czernichow S, van’t Hooft F, Axelsson T, Pedersen O, Hansen T, Sørensen TIA, Hebebrand J, Kere J, Dahlman-Wright K, Hamsten A, Clement K, Dahlman I. Genome wide association study identifies KCNMA1 contributing to human obesity. BMC Medical Genomics. 2011;4:51.

Johnson W, Kyvik KO, Skytthe A, Deary IJ, Sørensen TIA. Education modifies genetic and environmental influences on BMI. PLoS One. 2011;6:e16290.

Kilpeläinen TO, Qi L, Brage S,.........., Sørensen TIA,..........,  Ekelund U, Franks PW, Loos R. Physical activity attenuates the influence of FTO variants on obesity risk: a meta-analysis of 218,166 adults and 19,268 children. PLoS Med. 2011;8:e1001116.

Knop J. The Danish longitudinal study of alcoholism 1978-2008. A clinical high-risk study. Dan Med Bull. 2011; 58: B4315

Kotronen A, Yki-Jarvinen H, Sevastianova K, Bergholm, Hakarainen R, Pietiläinen A, Juurinen K, Lundbom L, Sørensen TIA
. Comparison of the relative contributions of intra-abdominal and liver fat to components of the metabolic syndrome. Obesity. 2011;19:23-28.

Kring SII, Barefoot J, Brummett BH, Boyle SH, Siegler IC, Toubro S, Hansen T, Astrup A, Pedersen O, Williams RB, Sørensen TIA. Associations betweenAPOE variants and metabolic traits and the impact of psychological stress. PLoS One. 2011;6:e15745.

Manzardo AM, Madarasz,WV, Penick EC, Knop J, Mortensen EL, Sørensen HJ, Mahnken JD, Becker U, Nickel E, Gabrielli WF Jr. Effects of premature birth on the risk for alcoholism appear to be greater in males than females. J Stud Alcohol Drugs. 2011;72:390-398. 

Mutch DM, Pers TH, Temanni MR, Pelloux V, Marquez-Quinones A, Holst C, Martinez JA, Babalis D, van Baak MA, Handjieva-Darlenska T, Walker CG, Astrup A, Saris WHM, Langin D, Viguerie N, Zucker J-D, Clement K on behalf of the DiOGenes Project. A distinct adipose tissue gene expression response to caloric restrition predicts 6-mo weight maintenance in obese subjects. Am J Clin Nutr. 2011; 94:1399-1409. 

Nielsen BM & Nielsen MM, Jakobsen MU, Nielsen CJ,  Holst C, Larsen TM, Bendsen NT, Bysted A, Leth T,  Hougaard DM, Skogstrand K,  Astrup A, Sørensen TIA, Jess T. A cross-sectional study on trans fatty acids and risk markers of CHD among middle-aged men representing a broad range of BMI. Br J Nutr. 2011;160:1245-1252.

Nielsen LS, Danielsen K, Sørensen TIA. Short sleep duration as a possible cause of obesity – critical analysis of the epidemiological evidence. Obes Rev. 2011;12:78-92. 

Nøjgaard C, Becker U, Matzen P, Andersen JR, Holst C, Bendtsen F.Progression from acute to chronic pancreatitis: Prognostic factors, mortality,
and natural course. Pancreas 2011;40:1195-1200.

Oppert JM, Sørensen TIA, Hebebrand J, Woodward E, Blundell JE. Opportunities for European obesity research in the coming decade - a perspective from the European Association for the Study of Obesity (EASO). Obes Facts. 2011;4:425-426.

Parnas J, Raballo A, Handest P, Jansson L, Vollmer-Larsen A, Sæbye D.Self-experience in the early phases of schizophrenia: 5 year follow-up of the Copenhagen Prodromal Study. World Psychiatry 2011;10:200-204.

Paternoster L, Evans DM, Nohr EA, Holst C, Gaborieau V, Brennan P, Gjesing AP, Grarup N, Witte DR, Jørgensen T, Linneberg A, Lauritzen T, Sandbaek A, Hansen T, Pedersen O, Elliot KS, Kemp JP, Pourcain B St, McMahon G, Zelenika D, Hager J, Lathrop M, Timpson NJ, Smith GD, Sørensen TIA. Genome-wide population-based association study of extremely overweight young adults – the GOYA study. PLoS One. 2011;6:e24303.

Pedersen P, Baker JL, Henriksen TB, Lissner L, Heitmann BL, Sørensen TIA, Nohr EA. Influence of psychosocial factors on postpartum weight retention. Obesity. 2011;19:639-646.

Pers TH, Hansen NT, Lage K, Koefoed P, Dworzynski P, Miller ML, Flint TJ, Mellerup E, Dam H, Andreassen OA, Djurovic S, Melle I, Børglum AD, Werge T, Purcell S, Ferreira MA, Kouskoumvekaki I, Workman CT, Hansen T, Mors O, Brunak S. Meta-analysis of heterogeneous data sources for genome-scale identification of risk genes in complex phenotypes. Gen Epidemiol. 2011;35:318-332.

Petersen L, Sørensen TIA.The Danish Adoption Register. Scand J Pub Health. 2011;39 (Suppl 7):83-86.

Petersen L, Sørensen TIA. Studies based on the Danish Adoption Register. Scand J Pub Health. 2011;39 (Suppl 7):191-195.

Raballo A, Sæbye D, Parnas J. Looking at the schizophrenia spectrum through the prism of self-disorders: An empirical study. Schizophr Bull. 2011;37:344-351. 

Risnes KR, Vatten LJ, Baker JL, Jameson K, Sovio U, Kajantie E, Osler M, Morley R, Jokela M, Painter RC, Sundh V, Jacobsen GW, Eriksson JG, Sørensen TIA, Bracken MB. Birthweight and mortality in adulthood; a systematic review and meta-analysis. Int J Epidemiol. 2011;40:647-661.

Rokholm B, Silventoinen K, Ängquist L, Skytthe A, Kyvik KO, Sørensen TIA. Increased genetic variance of BMI with a higher prevalence of obesity. PLoS One. 2011;6:e20816.

Rokholm B, Silventoinen K, Tynelius P, Gamborg M, Sørensen TIA, Rasmussen F. Increasing genetic variance of body mass index during the Swedish obesity epidemic. PLoS One. 2011;6:e27135 

Romaguera D, Angquist L, Du H, Jakobsen MU, Forouhi NG, Halkjær J, Feskens EJ, van der A DL, Masala G, Steffen A, Palli D, Wareham NJ, Overvad K, Tjønneland A, Boeing H, Riboli E. Sørensen TIA. Food composition of the diet in relation to changes in waist circumference adjusted for body mass index. PLoS One. 2011;6:e23384. 

Ruesten A von, Steffen A, Floegel A, van der A DL, Masala G, Tjønneland A, Halkjaer J, Palli D, Wareham N, Loos RJF, Sørensen TIA, Boeing H. Trend in obesity prevalence in European adult cohort populations during follow-up since 1996 and their predictions to 2015. PLoS ONE 2011;6:e27455.

Santos JL, De la Cruz R, Holst C, Grau K, Naranjo C, Maiz A, Astrup A, Saris WHM, Macdonald I, Oppert J-M, Hansen T, Pedersen O, Sørensen TIA, Martinez A, NUGENOB Consortium. Allelic variants of melanocortin 3 receptor gene (MC3R) and weight loss in obesity: A randomized trial of hypo-energetic high- versus low-fat diets. PLoS One. 2001;6:e19934.

Sluik D, Boeing H, Montonen J, Pischon T, Kaaks R, Teucher B, Tjønneland A, Halkjaer J, Berentzen TL, Overvad K, Arriola L, Ardanaz E, Bendinelli B, Grioni S, Tumino R, Sacerdote C, Mattiello A, Spijkerman AM, van der A DL, Beulens JW, van der Schouw YT, Nilsson PM, Hedblad B Rolandsson , Franks PW, Nöthlings U. Associations between general and abdominal adiposity and mortality in individuals with diabetes mellitus. Am J Epidemiol. 2011;174:22-34.

Stegger JG, Schmidt EB, Obel T, Berentzen TL, Tjønneland A, Sørensen TIA, Overvad K. Body composition and body fat distribution in relation to later risk of acute myocardial infarction: a Danish follow-up study. Int J Obes. 2011;35:1433-1441.

Sørensen HJ, Mortensen EL, Reinisch JM, Mednick SA. A prospective study of smoking in young women and risk of later psychiatric hospitalization. Nord J Psychiatry. 2011;65:3-8.

Sørensen HJ, Manzardo AM, Knop J, Penick EC, Madarasz W, Nickel EJ, Becker U, Mortensen EL. The contribution of parental alcohol use disorders and other psychiatric illness to the risk of alcohol use disorders in the offspring. Alcohol Clin Exp Res. 2011;35:1315-1320. 

Sørensen TIA. Obesity defined as excess storage of inert triglycerides - so we need a paradigm shift? [editorial] Obes Facts. 2011;4:91-94.

Sørup S, Villumsen M, Ravn H, Benn CS, Sørensen TIA, Aaby P, Jess T, Roth A. Smallpox vaccination and all-cause infectious disease hospitalisation: A Danish register-based cohort study. Int J Epidemiol. 2011;40:955-963.

Tanentsapf I, Heitmann BL and Adegboye RA. Systematic review of clinical trials on dietary interventions to to prevent excessive weight gain during pregnancy among normal weight, overweight and obse women. BMC Pregnancy childbirth. 2011; 11:81: 1 - 37.

Tang-Péronard JL, Andersen HR, Jensen TR, Heitmann BL. Endocrine- disrupting chemicals and obesity development in humans. A review. Obes Rev. 2011;12:622-636.

Vámosi ME, Heitmann BL, Thinggaard M, Kyvik KO. Parental care in childhood and obesity in adulthood: A study among twins. Obesity. 2011;19:1445-1450. 

Vedtofte MS, Jakobsen MU, Lauritzen L, Heitmann BL. Dietary a-linolenic acid, linoleic acid and n-3 long-chain polyunsaturated fatty acid and risk of coronary heart disease. Am J Clin Nutr. 2011; 94:1097-1103.

Verdich C, Barbe P, Petersen M, Grau K, Ward L, Macdonald I, Sørensen TIA, Oppert J-M. Changes in body composition during weight loss in obese subjects in the NUGENOB study: Comparison of bioelectrical impedance vs. dual-energy X-ray absorptiometry. Diabet Metab. 2011;37:222-229. 

Wang P, Holst C, Andersen MR, Astrup A, Bouwman FG, van Otterdijk S, Wodzig WKWH, van Baak MA, Larsen TM, Jebb SA, Kafatos A, Pfeiffer AFH, Martinez JA, Handjieva-Darlenska T, Kunesova M, Saris WHM, Mariman ECM. Blood profile of proteins and steroid hormones predicts
weight change after weight loss with interactions of dietary protein level and glycemic index. PLoS One. 2011;6e16773.

Wildenschild C, Kjøller M, Sabroe S, Erlandsen M, Heitmann BL. Change in the prevalence of obesity and use of health care in Denmark: an observational study. Clin Epidemiol. 2011;3:31-41. 

Zimmermann E, Anty R, Tordjman J, Verrijken A, Gual P, Tran A, Iannelli A, Gugenheim J, Bedossa P, Francque S, Le Marchand-Brustel Y, Clement K, Van Gaal L, Sørensen TIA, Jess T. C-reactive protein levels in relation to various features of non-alcoholic fatty liver disease among obese patients. J Hepatol. 2011;55:660-665. 

Zimmermann E, Skogstrand K, Hougaard DM, Astrup A, Hansen T, Pedersen O, Sørensen TIA, Jess T. Influences of the common FTO rs9939609 variant on inflammatory markers throughout a broad range of body mass index. PLoS One. 2011;6:e15958.

Zimmermann E, Holst C, Sørensen TIA. Lifelong doubling of mortality in men entering adult life as obese. Int J Obes. 2011; 35:1193-1199.

Zimmermann E, Holst C, Sørensen TIA. Morbidity, including fatal morbidity, throughout life in men entering adult life as obese. PLoS One.  2011;6:e18546. 

Miscellaneous

Heitmann BL. Evidens i fedmeforebyggelsen. Månedsskrift for Almen Praksis. - april 2011.

Seeger C, Heitmann BL. Forebyggelse [Kap 6] I: Svendsen OL, Astrup A, Hansen GS. (eds) Adipositas – sygdom, behandling og organisation. Munksgaard 2011:115-124.

Sørensen TIA, Andersen PK. Clinical epidemiology and statistical challenges in defining, recording and analyzing endpoints (Lecture 5). In: Franchis R de (Ed). Portal Hypertension V. Proceedings of the 5th Baveno International Consensus Workshop. Blackwell Publishing 2011:46-55.

Sørensen TIA. The enigmas of obesity. Public Service Review: European Science & Technology;10:222-223.

[accompanied by: Haarder B. Haarder at work. Public Service Review: European Science & Technology;10:218-219].

Sørensen TIA. Forskning [Kap. 14] I: Svendsen OL, Astrup A, Hansen GS. (eds) Adipositas – sygdom, behandling og organisation. Munksgaard 2011: 283-292. 

Sørensen TIA. Fedmens gåder. Videnskab dk 30. november 2011 kl. 11:07.

World Health Organization. Waist circumference and waist-hip ratio: Report of a WHO expert consultation [Sørensen TIA member of consultation] , Geneva, 8-11 December, 2008 World Health Organization 2011, pp 1-39.

Updated by Birgitte M Skogstad

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