With a strong interest and experience in
pharmacoepidemiology, quantitative methods and causal inference Mikkel is part
of the Phase IV unit at Center for Clinical Research and Prevention.
Mikkel (MSc Public Health) has a PhD in epidemiology
(2014) on the topic of reconciling conflicting evidence from randomized,
controlled trials and observational studies. The discussion of RCTs versus
observational studies, mimicking trials in observational data and the utility
of the respective study designs are all topics that motivate Mikkel.
Mikkel has insight in the pharmaceutical industry from
employment at Novo Nordisk A/S (www.novonordisk.com).
Mikkel has worked with the use of observational/real world data in drug
development through his participation in the pan-European research consortium GETREAL – real world data in drug
A systematic literature review on the
efficacy-effectiveness gap: comparison of randomized controlled trials and
observational studies of glucose-lowering drugs. Ankarfeldt MZ,
Adalsteinsson E, Groenwold RH, Ali MS, Klungel OH. Clin Epidemiol. 2017 Jan 23;9:41-51.
Assessment of channeling bias among
initiators of glucose-lowering drugs: A UK cohort study. Ankarfeldt MZ,
Thorsted BL, Groenwold RH, Adalsteinsson E, Ali MS, Klungel OH. Clin Epidemiol.
2017 Jan 18;9:19-30.
The "Efficacy-Effectiveness Gap": Historical
Background and Current Conceptualization. Nordon C, Karcher H, Groenwold RH, Ankarfeldt
MZ, Pichler F, Chevrou-Severac H, Rossignol M, Abbe A, Abenhaim L; GetReal
consortium. Value Health. 2016 Jan;19(1):75-81.
Body characteristics, dietary protein and
body weight regulation. Reconciling conflicting results from intervention and
observational studies? Ankarfeldt MZ, Ängquist L, Stocks T, Jakobsen MU,
Overvad K, Halkjær J, Saris WH, Astrup A, Sørensen TI. PLoS One. 2014 Jul
Comment on "Limitations of observational
evidence: implications for evidence-based dietary recommendations". Ankarfeldt
MZ. Adv Nutr. 2014 May 14;5(3):293.