New 10 million DKK grant received from Novo Nordisk Foundation

Senior researcher ​Jennifer L. Baker has received an Ascending Investigator Grant in Endocrinology and Metabolism from the Novo Nordisk Foundation of DKK 9.999.878 for the project "Lifecourse and intergenerational pathways to child and adult cardiometabolic health".


Type 2 diabetes and cardiovascular disease are leading causes of death and disability in Denmark. Overweight and obesity from childhood onwards are a major contributor to these cardiometabolic diseases, and levels are too high in Danish children and adults. Further, growth during fetal life, familial and intergenerational inheritance, social determinants of health and health policies also contribute to the risk of cardiometabolic disease. Nonetheless, an integrated understanding of how these factors operate on risk across the lifecourse from early life to disease is lacking. In the proposed research we will determine how growth during fetal life and childhood is associated with cardiometabolic disease risk factors at child ages and hard endpoint  cardiometabolic disease at adult ages. We will examine genetic and intergenerational contributions to disease risk, effects of social determinants of health and if policy changes affecting school-based health care provision impact later disease.

This novel cross-disciplinary project will provide etiologic insights into the early origins of disease, direct at which ages and stages of life there are suitable targets for prevention and intervention, and identify potentially effective policy changes, and thus increase opportunities for protecting and improving cardiometabolic health.



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