With a strong interest and experience in pharmacoepidemiology, quantitative methods and causal inference Mikkel is part of the Phase IV unit at Center for Clinical Research and Prevention.
Mikkel (MSc Public Health) has a PhD in epidemiology (2014) on the topic of reconciling conflicting evidence from randomized, controlled trials and observational studies. The discussion of RCTs versus observational studies, mimicking trials in observational data and the utility of the respective study designs are all topics that motivate Mikkel.
Mikkel has insight in the pharmaceutical industry from employment at Novo Nordisk A/S (www.novonordisk.com). Mikkel has worked with the use of observational/real world data in drug development through his participation in the pan-European research consortium GETREAL – real world data in drug development (www.imi-getreal.eu).
A systematic literature review on the efficacy-effectiveness gap: comparison of randomized controlled trials and observational studies of glucose-lowering drugs. Ankarfeldt MZ, Adalsteinsson E, Groenwold RH, Ali MS, Klungel OH. Clin Epidemiol. 2017 Jan 23;9:41-51.
Assessment of channeling bias among initiators of glucose-lowering drugs: A UK cohort study. Ankarfeldt MZ, Thorsted BL, Groenwold RH, Adalsteinsson E, Ali MS, Klungel OH. Clin Epidemiol. 2017 Jan 18;9:19-30.
The "Efficacy-Effectiveness Gap": Historical Background and Current Conceptualization. Nordon C, Karcher H, Groenwold RH, Ankarfeldt MZ, Pichler F, Chevrou-Severac H, Rossignol M, Abbe A, Abenhaim L; GetReal consortium. Value Health. 2016 Jan;19(1):75-81.
Body characteristics, dietary protein and body weight regulation. Reconciling conflicting results from intervention and observational studies? Ankarfeldt MZ, Ängquist L, Stocks T, Jakobsen MU, Overvad K, Halkjær J, Saris WH, Astrup A, Sørensen TI. PLoS One. 2014 Jul 3;9(7):e101134.
Comment on "Limitations of observational evidence: implications for evidence-based dietary recommendations". Ankarfeldt MZ. Adv Nutr. 2014 May 14;5(3):293.