Mathilde Marie Sloth has a bachelor's degree in public health from the University of Copenhagen and is a master's student. Mathilde is affiliated as a scholarstipendiat.

Mathilde was affiliated when writing her bachelor thesis about depression in adulthood and the subsequent risk of dementia in spring 2021 with Terese Sara Høj Jørgensen and Merte Osler as mentors. In January 2022 Mathilde and Emma Neble Larsen published their first article based on their bachelor thesis: Depression in adulthood and risk of dementia later in life: A Danish register-based cohort study of 595,828 men.